Amazing Medicinal Plant Kills Malignant Tumors and Destroys 70 Percent of Breast Cancer Cells
Jan 24, 2014 | Prevent Disease | Dr. Marianna Pochelli
Beyond limited empirical observations, not all medicinal plants have established scientific studies to support their effectiveness. However, in the case of Brucea javanica,
it is one of those plants in which scientific investigations have
provided enough evidence to prove that it has an impressive efficacy for
the treatment of cervical, bladder and pancreatic cancers. Its
selective toxicity has also been found to kill 70% of breast cancer
Oncologists are still at a loss to find methods of selectively killing
cancer cells through the standard protocols of treatment in chemotherapy and radiation. While damaging healthy cells is an inevitable process through most cytotoxic drugs, chemotherapy also triggers them to secrete a protein that sustains tumour growth and resistance to further treatment.
As more knowledge and research is being extended to
populations confined to conventional allopathic principles, the broad
categories of herbal and plant medicines are finally reaching the
mainstream. The effectiveness of medicinal plants and foods to treat
cancer is perhaps receiving the most widespread attention. Dietary anti-angiogenic foods
alone have sparked so much interest in the cancer community, that even
veteran Physicians are beginning to recommend them to cancer patients.
Brucea javanica (Brucea javanica (L.) Merr)
is one of those plants that needs far more recognition in this
catergory for its incredible ability to selectively kill cancer cells.
A shrub original from South-east Asia, and
occurs from Sri Lanka and India towards Indo-China, southern China,
Taiwan, Thailand and even northern
Australia, B. javanica has been the subject of
hundreds of studies and clinical trials, all of them aimed to better
understand two main key issues: First how effective this plant really
is; and secondly, if it is so effective, which active constituents are
responsible for its anti-cancer properties.
B. javanica is a monoecious or dioecious shrub
or small tree that can grow up to 10 m tall with soft-haired twigs and
leaves. It prefers open localities such as light secondary forests
and thickets, forest edges, ridges, and even occurring in sunny places
on sandy dunes and on limestone. It grows under both per-humid and
seasonal conditions from sea level up to 900 m altitude
For several millennia, herbal preparations and natural remedies from B. javanica
have been shown to be effective in treating many types of maladies
including malaria, and amoebiasis as well as cancer.
of the drugs currently in clinical use are of natural origin, however
many of these drugs become toxic with substantial side effects due to
the integration of artificial chemical compounds in their formulas.
B. javanica contains alkaloids (brucamarine, yatanine),
glycosides/quassinoids (brucealin, yatanoside A and B, kosamine,
bruceantin, bruceantarin, bruceantinol), and phenol (brucenol,
bruceolic acid). The seeds contain brusatol and bruceine. The pulp oil
contains fat, oleic acid, linoleic acid, stearic acid, and palmitoleic
acid. Fruit and leaves contain tannin.
To date, 153 compounds have been reported from the seeds and aerial
parts of Brucea javanica. Quassinoids are the main constituents of this
species. The extract of Brucea javanica and the isolated compounds,
specifically quassinoids exhibit various biological properties and are
well known for their antitumor effects, especially how they are
selectively toxic to cancer cells.
A study in the American Journal of Medical Science demonstrated that the aqueous extract from B. javanica and the induction of apoptosis by components of B. javanica is an indicated mechanism by which it kills cancer cells. The study found that B. javanica treatment lead to 70% cell death in breast cancer cells.
Another study in the American Journal of Chinese Medicine
from researchers at the Department of Urology, The First Affiliated
Hospital, Zhejiang University School of Medicine, Hongzhou, China,
found that B. javanica oil significantly induces programmed cell death of bladder cancer cells.
A study from the international journal Cancer Letters, researchers showed that brucein D (BD), a quassinoid found abundantly in B. javanica
fruit, inhibited the growth of three pancreatic cancer cell lines. They
provided experimental evidence to support the traditional use of B.
javanica fruit in cancer treatment, and render BD a promising candidate
for further development into anti-pancreatic cancer agent.
Yet another study in the International Journal of Molecular Medicine, demonstrated the antiproliferative and apoptotic activities of B. javanica
along with other herbal traditional Chinese medicines. They concluded
that the programmed cell death of cancer cells activated by specific
proteins was 5 times higher in cells treated with B. javanica.
Bruceantin, a contituent of B. javanica has also been found to interfere with the growth of leukemia, lymphoma, and myeloma cells.
Regardless of centuries of empirical observation as well as the scientifically documented evidence of B. javanica as a medicinal plant and bonafide anti-cancer potential, the World Health Organization (WHO) monographs of selected medicinal plants, claims that no medical uses for B. javanica are supported by clinical data.
Dr. Marianna Pochelli
is a Doctor of Naturopathic Medicine specializing in the treatment of
disease through superfoods and herbal strategies. She actively
promotes detoxification, colon cleansing, and a vegetarian lifestyle
using living foods as a platform to health.